Literature summary for 5.6.1.6 extracted from

Fang, X.; Song, Y.; Hirsch, J.; Galietta, L.J.; Pedemonte, N.; Zemans, R.L.; Dolganov, G.; Verkman, A.S.; Matthay, M.A.
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells (2006), Am. J. Physiol. Lung Cell Mol. Physiol., 290, L242-L249.

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Application

Application	Comment	Organism
additional information	plays a role in cAMP-mediated apical-vasolateral ion and fluid transport	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
CFTRinh-172	inhibits cAMP stimulated but not basal fluid transport	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bronchial epithelium	expression comparable to the expression in alveolar epithelial type II cell	Homo sapiens	-
lung	-	Homo sapiens	-
additional information	alveolar epithelial type II cell, expression comparable to the expression in bronchial epithelial cell	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
CFTR	-	Homo sapiens

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Release 2023.1 (January 2023)