Cloned (Comment) | Organism |
---|---|
expression of a fusion protein of glutathione S-transferase and nucleotide binding domain 1 | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
the MW of the fusion protein of glutathione S-transferase and nucleotide binding domain 1 determined by SDS-PAGE is 70000 Da | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + closed Cl- channel | Homo sapiens | - |
ADP + phosphate + open Cl- channel | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | protein kinase A phosphorylates a group of R-domain serine residues in nucleotide binding domain 1. This causes the fusion protein to dimerize, to exhibit cooperative ATP binding and hydrolysis, and to be subject to regulation by nucleotide binding domain 2 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + closed Cl- channel | - |
Homo sapiens | ADP + phosphate + open Cl- channel | - |
? | |
ATP + H2O + closed Cl- channel | protein kinase A phosphorylates a group of R-domain serine residues in nucleotide binding domain 1. This causes the fusion protein to dimerize, to exhibit cooperative ATP binding and hydrolysis, and to be subject to regulation by nucleotide binding domain 2 | Homo sapiens | ADP + phosphate + open Cl- channel | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the MW of the fusion protein of glutathione S-transferase and nucleotide binding domain 1 determined by SDS-PAGE is 70000 Da | Homo sapiens |