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BRENDA support

Literature summary for 5.6.1.6 extracted from

  • Sugita, M.; Yue, Y.; Foskett, J.K.
    CFTR Cl- channel and CFTR-associated ATP channel: distinct pores regulated by common gates (1998), EMBO J., 17, 898-908.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information phosphorylation dependent and nucleotide-hydrolysis dependent gating of CFTR is directly involved in gating of an associated ATP channel Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + closed Cl- channel chloride channel Homo sapiens ADP + phosphate + open Cl- channel
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