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Literature summary for 5.6.1.5 extracted from

  • Zhu, Y.; Wang, W.L.; Yu, D.; Ouyang, Q.; Lu, Y.; Mao, Y.
    Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome (2018), Nat. Commun., 9, 1360 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + polypeptide Homo sapiens
-
ADP + phosphate + unfolded polypeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
NeutrAvidin agarose column chromatography and Superose 6 gel filtration Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + polypeptide
-
Homo sapiens ADP + phosphate + unfolded polypeptide
-
?

Subunits

Subunits Comment Organism
heterohexamer
-
Homo sapiens

Synonyms

Synonyms Comment Organism
AAA-ATPase unfoldase
-
Homo sapiens
Rpt
-
Homo sapiens