Literature summary for 5.6.1.5 extracted from

Zhang, F.; Su, K.; Yang, X.; Bowe, D.B.; Paterson, A.J.; Kudlow, J.E.
O-GlcNAc modification is an endogenous inhibitor of the proteasome (2003), Cell, 115, 715-725.

Search for more literature for 5.6.1.5

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
O-GlcNac transferase	inhibition of Rpt2 by O-GlcNAc leads to a decrease in proteasome activity	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + polypeptide	Homo sapiens	-	ADP + phosphate + unfolded polypeptide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant Rpt2	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + polypeptide	-	Homo sapiens	ADP + phosphate + unfolded polypeptide	-	?

Synonyms

Synonyms	Comment	Organism
Rpt2	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)