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Literature summary for 5.6.1.5 extracted from

  • Ito, N.; Tomizawa, K.; Tanaka, K.; Matsui, M.; Kendrick, R.E.; Sato, T.; Nakagawa, H.
    Characterization of 26S proteasome alpha- and beta-type and ATPase subunits from spinach and their expression during early stages of seedling development (1997), Plant Mol. Biol., 34, 307-316.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cDNAs encoding 26Sproteasome subunits, genes SOPSC8, SOPSC1 and SOPRS7 from the 19/22S regulatory complex Spinacia oleracea
human ATPase subunit MSS1 gene used for screening Homo sapiens
several subunit genes of the 20S catalytic core and the 19/22S regulatory complex have been isolated Solanum lycopersicum
several subunit genes of the 20S catalytic core and the 19/22S regulatory complex have been isolated Oryza sativa
several subunit genes of the 20S catalytic core and the 19/22S regulatory complex have been isolated, MBP1 gene of the 19/22S regulatory complex cloned Arabidopsis sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + polypeptide Homo sapiens
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Rattus norvegicus
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Saccharomyces cerevisiae
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Spinacia oleracea
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Xenopus laevis
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Arabidopsis sp.
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Solanum lycopersicum
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Oryza sativa
-
ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide Thermoplasma sp.
-
ADP + phosphate + unfolded polypeptide
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis sp.
-
-
-
Homo sapiens
-
-
-
Oryza sativa
-
rice
-
Rattus norvegicus
-
rat
-
Saccharomyces cerevisiae
-
-
-
Solanum lycopersicum
-
-
-
Spinacia oleracea
-
-
-
Thermoplasma sp.
-
acidophilum
-
Xenopus laevis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
26Sproteasome Spinacia oleracea

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Homo sapiens
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Rattus norvegicus
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Saccharomyces cerevisiae
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Spinacia oleracea
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Xenopus laevis
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Arabidopsis sp.
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Solanum lycopersicum
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Oryza sativa
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Thermoplasma sp.

Source Tissue

Source Tissue Comment Organism Textmining
cotyledon
-
Spinacia oleracea
-
hypocotyl
-
Spinacia oleracea
-
root
-
Spinacia oleracea
-
seed
-
Spinacia oleracea
-
seedling
-
Spinacia oleracea
-
shoot
-
Spinacia oleracea
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + polypeptide
-
Homo sapiens ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Rattus norvegicus ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Saccharomyces cerevisiae ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Spinacia oleracea ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Xenopus laevis ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Arabidopsis sp. ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Solanum lycopersicum ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Oryza sativa ADP + phosphate + unfolded polypeptide
-
?
ATP + H2O + polypeptide
-
Thermoplasma sp. ADP + phosphate + unfolded polypeptide
-
?

Synonyms

Synonyms Comment Organism
26S proteasome
-
Homo sapiens
26S proteasome
-
Rattus norvegicus
26S proteasome
-
Saccharomyces cerevisiae
26S proteasome
-
Spinacia oleracea
26S proteasome
-
Xenopus laevis
26S proteasome
-
Thermoplasma sp.