Cloned (Comment) | Organism |
---|---|
cDNAs encoding 26Sproteasome subunits, genes SOPSC8, SOPSC1 and SOPRS7 from the 19/22S regulatory complex | Spinacia oleracea |
human ATPase subunit MSS1 gene used for screening | Homo sapiens |
several subunit genes of the 20S catalytic core and the 19/22S regulatory complex have been isolated | Solanum lycopersicum |
several subunit genes of the 20S catalytic core and the 19/22S regulatory complex have been isolated | Oryza sativa |
several subunit genes of the 20S catalytic core and the 19/22S regulatory complex have been isolated, MBP1 gene of the 19/22S regulatory complex cloned | Arabidopsis sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + polypeptide | Homo sapiens | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Rattus norvegicus | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Saccharomyces cerevisiae | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Spinacia oleracea | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Xenopus laevis | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Arabidopsis sp. | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Solanum lycopersicum | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Oryza sativa | - |
ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | Thermoplasma sp. | - |
ADP + phosphate + unfolded polypeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis sp. | - |
- |
- |
Homo sapiens | - |
- |
- |
Oryza sativa | - |
rice | - |
Rattus norvegicus | - |
rat | - |
Saccharomyces cerevisiae | - |
- |
- |
Solanum lycopersicum | - |
- |
- |
Spinacia oleracea | - |
- |
- |
Thermoplasma sp. | - |
acidophilum | - |
Xenopus laevis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
26Sproteasome | Spinacia oleracea |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Homo sapiens | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Rattus norvegicus | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Saccharomyces cerevisiae | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Spinacia oleracea | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Xenopus laevis | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Arabidopsis sp. | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Solanum lycopersicum | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Oryza sativa | |
ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide | belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome | Thermoplasma sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cotyledon | - |
Spinacia oleracea | - |
hypocotyl | - |
Spinacia oleracea | - |
root | - |
Spinacia oleracea | - |
seed | - |
Spinacia oleracea | - |
seedling | - |
Spinacia oleracea | - |
shoot | - |
Spinacia oleracea | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + polypeptide | - |
Homo sapiens | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Rattus norvegicus | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Saccharomyces cerevisiae | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Spinacia oleracea | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Xenopus laevis | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Arabidopsis sp. | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Solanum lycopersicum | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Oryza sativa | ADP + phosphate + unfolded polypeptide | - |
? | |
ATP + H2O + polypeptide | - |
Thermoplasma sp. | ADP + phosphate + unfolded polypeptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
26S proteasome | - |
Homo sapiens |
26S proteasome | - |
Rattus norvegicus |
26S proteasome | - |
Saccharomyces cerevisiae |
26S proteasome | - |
Spinacia oleracea |
26S proteasome | - |
Xenopus laevis |
26S proteasome | - |
Thermoplasma sp. |