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Literature summary for 5.6.1.3 extracted from

  • Hu, L.; Hu, H.; Li, Z.
    A kinetoplastid-specific kinesin is required for cytokinesis and for maintenance of cell morphology in Trypanosoma brucei (2012), Mol. Microbiol., 83, 565-578.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.3

Cloned(Commentary)

Cloned (Comment) Organism
GST fusions of TbKIN-C and the motor domain of TbKIN-C expressed in Escherichia coli BL21 Trypanosoma brucei

Protein Variants

Protein Variants Comment Organism
K196A motor domain, no activity Trypanosoma brucei

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei Q57XC6
-
-
Trypanosoma brucei 427 Q57XC6
-
-

Purification (Commentary)

Purification (Comment) Organism
glutathione Sepharose, only motor domains are soluble Trypanosoma brucei

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Trypanosoma brucei ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Trypanosoma brucei 427 ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?

Synonyms

Synonyms Comment Organism
kinetoplastid specific kinesin
-
 Trypanosoma brucei
TbKIN-C
-
 Trypanosoma brucei

General Information

General Information Comment Organism
physiological function cytokinesis, maintenance of cell morphology Trypanosoma brucei