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Literature summary for 5.6.1.3 extracted from

  • Zhang, M.; Zhang, B.; Qian, Q.; Yu, Y.; Li, R.; Zhang, J.; Liu, X.; Zeng, D.; Li, J.; Zhou, Y.
    Brittle Culm 12, a dual-targeting kinesin-4 protein, controls cell-cycle progression and wall properties in rice (2010), Plant J., 63, 312-328.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.3

Protein Variants

Protein Variants Comment Organism
additional information bc12 mutants display dwarfism resulting from a significant cell number reduction and brittleness due to an alteration in cellulose microfibril orientation and wall composition Oryza sativa Japonica Group

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Oryza sativa Japonica Group 5737
-
nucleus
-
 Oryza sativa Japonica Group 5634
-

Organism

Organism UniProt Comment Textmining
Oryza sativa Japonica Group
-
-
-

Purification (Commentary)

Purification (Comment) Organism
the purified protein co-sediments with microtubules, but the majority of the protein remains in the supernatant in the absence of microtubules, indicating that the motor domain of BC12 binds microtubules Oryza sativa Japonica Group

Source Tissue

Source Tissue Comment Organism Textmining
additional information BC12 is mainly expressed in tissues undergoing cell division and secondary wall thickening Oryza sativa Japonica Group
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 the enzyme activity is proportional to the amount of microtubules. The motor domain with the stalk region shows higher enzyme activity than the motor domain alone in the presence of 0.04 mg of microtubules, suggesting that BC12 has microtubule-dependent ATPase activity and that the neck linker is critial for this activity Oryza sativa Japonica Group

Synonyms

Synonyms Comment Organism
BC12
-
 Oryza sativa Japonica Group
BC12 Brittle Culm12, a gene coding for kinesin-4 protein Oryza sativa Japonica Group
Brittle Culm12
-
 Oryza sativa Japonica Group
Brittle Culm12 a gene coding for kinesin-4 protein Oryza sativa Japonica Group

General Information

General Information Comment Organism
physiological function BC12 functions as a dual-targeting kinesin protein and is implicated in cell-cycle progression, cellulose microfibril deposition and wall composition in the monocot plant rice. Perturbation of BC12 produces defects in cell number/plant height and mechanical properties. BC12 has a conserved ATPase-driven motor domain that is required for bindung to and moving along the microtubules Oryza sativa Japonica Group