Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.6.1.3 extracted from

  • Martinez, N.W.; Xue, X.; Berro, R.G.; Kreitzer, G.; Resh, M.D.
    Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein (2008), J. Virol., 82, 9937-9950.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.3

Activating Compound

Activating Compound Comment Organism Structure
microtubule
-
 Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-1 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information disrupting the function of kinesin KIF4 slows temporal progression of Gag through its trafficking intermediates and inhibits virus-like particle production Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens KIF4 regulates Gag stability and trafficking ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Homo sapiens ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?
additional information KIF4 regulates Gag stability and trafficking Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
KIF4 a plus-end-directed, microtubule-stimulated ATPase Homo sapiens
KIF4A
-
 Homo sapiens