Literature summary for 5.6.1.3 extracted from

Helenius, J.; Brouhard, G.; Kalaidzidis, Y.; Diez, S.; Howard, J.
The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends (2006), Nature, 441, 115-119.

Search for more literature for 5.6.1.3

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	Homo sapiens	-	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	recombinantly expressed in Spodoptera frugiperda	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	-	Homo sapiens	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?
ATP + H2O + a kinesin associated with a microtubule at position n	MCAK moves along the microtubule lattice in one-dimensional random walk	Homo sapiens	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Synonyms

Synonyms	Comment	Organism
depolymerizing kinesin MCAK	-	Homo sapiens
kinesin-13	-	Homo sapiens

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Release 2023.1 (January 2023)