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Literature summary for 5.6.1.3 extracted from

  • Kwok, B.H.; Kapitein, L.C.; Kim, J.H.; Peterman, E.J.; Schmidt, C.F.; Kapoor, T.M.
    Allosteric inhibition of kinesin-5 modulates its processive directional motility (2006), Nat. Chem. Biol., 2, 480-485.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
baculovirus expression Xenopus laevis

Inhibitors

Inhibitors Comment Organism Structure
monastrol suppresses the directional processive motility of microtubule-bound Eg5 Xenopus laevis

Organism

Organism UniProt Comment Textmining
Xenopus laevis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Xenopus laevis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Xenopus laevis ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?

Synonyms

Synonyms Comment Organism
Eg5
-
Xenopus laevis
kinesin-5
-
Xenopus laevis