Literature summary for 5.6.1.3 extracted from

Varga, V.; Helenius, J.; Tanaka, K.; Hyman, A.A.; Tanaka, T.U.; Howard, J.
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner (2006), Nat. Cell Biol., 8, 957-962.

Search for more literature for 5.6.1.3

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	Saccharomyces cerevisiae	Kip3p destabilizes microtubules by depolymerizing them. Kip3p disassembles microtubules exclusively at the plus end and depolymerizes longer microtubules faster than shorter ones	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	recombinantly expressed in Sf9 cells	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	-	Saccharomyces cerevisiae	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?
ATP + H2O + a kinesin associated with a microtubule at position n	Kip3p destabilizes microtubules by depolymerizing them. Kip3p disassembles microtubules exclusively at the plus end and depolymerizes longer microtubules faster than shorter ones	Saccharomyces cerevisiae	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Synonyms

Synonyms	Comment	Organism
kinesin-8	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)