Literature summary for 5.6.1.3 extracted from

Dastidar, P.G.; Majumder, S.; Lohia, A.
Eh Klp5 is a divergent member of the kinesin 5 family that regulates genome content and microtubular assembly in Entamoeba histolytica (2006), Cell. Microbiol., 9, 316-328.

Search for more literature for 5.6.1.3

Inhibitors

Inhibitors	Comment	Organism	Structure
monastrol	0.2 mM, 25% inhibition. Compared to vertebrate Eg5, Eh Klp5 is less sensitive to monastrol	Entamoeba histolytica

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	Entamoeba histolytica	Eh Klp5 is a divergent member of the kinesin 5 family that regulates genome content and microtubular assembly	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Organism

Organism	UniProt	Comment	Textmining
Entamoeba histolytica	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	-	Entamoeba histolytica	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?
ATP + H2O + a kinesin associated with a microtubule at position n	Eh Klp5 is a divergent member of the kinesin 5 family that regulates genome content and microtubular assembly	Entamoeba histolytica	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Synonyms

Synonyms	Comment	Organism
Eh Klp5	-	Entamoeba histolytica

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)