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Literature summary for 5.6.1.3 extracted from

  • Lane, J.D.; Allan, V.J.
    Microtubule-based endoplasmic reticulum motility in Xenopus laevis: activation of membrane-associated kinesin during development (1999), Mol. Biol., 10, 1909-1922.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm axoplasm Doryteuthis pealeii 5737
-
cytosol
-
Xenopus laevis 5829
-
cytosol
-
Doryteuthis pealeii 5829
-
membrane associated Xenopus laevis 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Xenopus laevis
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Doryteuthis pealeii
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Tetrahymena sp.
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Xenopus laevis the rate of ER tubule extensions toward microtubule plus ends is lower than minus end-directed motility. Initiation of plus end-directed ER motility in somatic cytosol is likely to occur via activation of membrane-associated kinesin ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Xenopus laevis
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Doryteuthis pealeii
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Tetrahymena sp.
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?

Organism

Organism UniProt Comment Textmining
Doryteuthis pealeii
-
-
-
Tetrahymena sp.
-
-
-
Xenopus laevis
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Xenopus laevis
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Doryteuthis pealeii
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Tetrahymena sp.

Source Tissue

Source Tissue Comment Organism Textmining
egg
-
Xenopus laevis
-
embryo
-
Xenopus laevis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Xenopus laevis ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Doryteuthis pealeii ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Tetrahymena sp. ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n the rate of ER tubule extensions toward microtubule plus ends is lower than minus end-directed motility. Initiation of plus end-directed ER motility in somatic cytosol is likely to occur via activation of membrane-associated kinesin Xenopus laevis ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Xenopus laevis GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Doryteuthis pealeii GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Tetrahymena sp. GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?