Cloned (Comment) | Organism |
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expression of green fluorescent protein/dynein intermediate chain isoforms fusion proteins in PC12 cells | Rattus norvegicus |
Protein Variants | Comment | Organism |
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additional information | expression of green fluorescent protein/dynein intermediate chain isoforms fusion proteins in PC12 cells. Intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms | ? | - |
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Organism | UniProt | Comment | Textmining |
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Rattus norvegicus | - |
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- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms | Rattus norvegicus | ? | - |
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Subunits | Comment | Organism |
---|---|---|
More | dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms | Rattus norvegicus |