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Literature summary for 5.6.1.2 extracted from

  • Takahashi, Y.; Edamatsu, M.; Toyoshima, Y.Y.
    Multiple ATP-hydrolyzing sites that potentially function in cytoplasmic dynein (2004), Proc. Natl. Acad. Sci. USA, 101, 12865-12869.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information truncated mutant enzymes lacking one or more AAA –ATPase associated with diverse activities – modules. One AAA module is insufficient for ATP hydrolysis, and the adjacent molecule facing the ATP-binding site is necessary for ATP-hydrolyzing activity Saccharomyces cerevisiae
R2209A mutation in AAA1 module, reduced ATPase activity Saccharomyces cerevisiae
R2911A mutation in AAA3 module, reduced ATPase activity Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
recombinant enzymes expressed in Escherichia coli
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