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Literature summary for 5.6.1.2 extracted from

  • Fujiwara, A.; Yokokawa, M.; Hino, A.; Yasumasu, I.
    Inhibition by palmitoyl CoA of dynein ATPase from sea urchin spermatozoa (1982), J. Biochem., 92, 441-447.
    View publication on PubMed
Search for more literature for 5.6.1.2

Activating Compound

Activating Compound Comment Organism Structure
myristoyl-CoA activats at 0.01 mM, inhibits at 0.04 mM Hemicentrotus pulcherrimus
palmitoyl-CoA activates dynein between 2 and 0.01 mM, inhibites at 0.04 mM Hemicentrotus pulcherrimus

Inhibitors

Inhibitors Comment Organism Structure
myristoyl-CoA 0.040 mM, activates at 0.010 mM Hemicentrotus pulcherrimus
palmitoyl-CoA noncompetitive inhibition of 14S dynein ATPase at 0.040 mM, bovine serum albumin (1mg/ml) and spermine (0.1 and 1 mM) reverse inhibition Hemicentrotus pulcherrimus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a dynein associated with a microtubule at position n Hemicentrotus pulcherrimus
-
 ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

Organism UniProt Comment Textmining
Hemicentrotus pulcherrimus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.23
-
 14S dynein ATPase Hemicentrotus pulcherrimus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a dynein associated with a microtubule at position n
-
 Hemicentrotus pulcherrimus ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?