Literature summary for 5.5.1.4 extracted from

Azam, S.S.; Sarfaraz, S.; Abro, A.
Comparative modeling and virtual screening for the identification of novel inhibitors for myo-inositol-1-phosphate synthase (2014), Mol. Biol. Rep., 41, 5039-5052 .

Inhibitors

Inhibitors	Comment	Organism
(1R,2R)-4-methylcyclohex-4-ene-1,2-dicarboxylic acid	ZINC04728953	Homo sapiens
(1R,2S,3S,6R)-3,4-dimethyl-6-(2-methylprop-1-en-1-yl)cyclohex-4-ene-1,2-dicarboxylic acid	ZINC04023366	Homo sapiens
(1R,6S)-bicyclo[4.1.0]heptane-7,7-dicarboxylic acid	ZINC03852384	Homo sapiens
(2R)-2-benzylbutanedioic acid	ZINC00291743	Homo sapiens
(2R)-2-pentylbutanedioic acid	ZINC03033114	Homo sapiens
(2R,5R)-2-ethenyl-5,6-dihydroxy-2,6-dimethylheptanoic acid	ZINC35464863	Homo sapiens
(2R,5R)-2-methyl-5-(propan-2-yl)hexanedioic acid	ZINC39738114	Homo sapiens
(2R,5S)-2-ethenyl-5,6-dihydroxy-2,6-dimethylheptanoic acid	ZINC35464866	Homo sapiens
(2S)-2,3-diphenylpropanoic acid	ZINC00164149	Homo sapiens
(2S)-2-(prop-2-yn-1-yl)heptanoic acid	-	Homo sapiens
(2S)-2-[(5R)-2,5,6-trimethylcyclohepta-1,6-dien-1-yl]pentanedioic acid	ZINC72320447	Homo sapiens
(2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid	ZINC38141759	Homo sapiens
(2S,5R)-2-methyl-5-(propan-2-yl)hexanedioic acid	ZINC39738116	Homo sapiens
(2S,5S)-2-ethenyl-5,6-dihydroxy-2,6-dimethylheptanoic acid	ZINC35464860	Homo sapiens
(2S,5S)-2-methyl-5-(propan-2-yl)hexanedioic acid	ZINC39738117	Homo sapiens
(3S)-3-(furan-2-yl)-6-methylheptanoic acid	ZINC02120167	Homo sapiens
(4S)-4-acetylheptanoic acid	ZINC02470134	Homo sapiens
2,2,5,7-tetramethyl-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid	ZINC00137063	Homo sapiens
2,4-dihydroxy-6-methylbenzoic acid	ZINC00901157	Homo sapiens
2-(2-methyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid	ZINC03844222	Homo sapiens
2-benzyl-2-hydroxy-3-phenylpropanoic acid	ZINC03844661	Homo sapiens
2-benzyl-2-methylbutanedioic acid	ZINC03844125	Homo sapiens
5-methyl-4-phenyl-2-(1H-pyrrol-1-yl)thiophene-3-carboxylic acid	ZINC03844214	Homo sapiens
methyl[(4-methylphenyl)methyl]propanedioic acid	ZINC03848645	Homo sapiens
N-[4-[(dihydroxyamino)sulfanyl]phenyl]-2-propylpentanamide	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-Glucose 6-phosphate	Homo sapiens	-	L-myo-Inositol 1-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9NPH2	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-Glucose 6-phosphate	-	Homo sapiens	L-myo-Inositol 1-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
MIP synthase	-	Homo sapiens
Myo-inositol-1-phosphate synthase	-	Homo sapiens