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Literature summary for 5.5.1.4 extracted from
- myo-Inositol-1-phosphate synthase from pine pollen: sulfhydryl involvement at the active site (1984), Arch. Biochem. Biophys., 231, 372-377.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| NH4+ | stimulates | Pinus ponderosa |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-deoxy-D-glucose 6-phosphate | - |
Pinus ponderosa | |
| NEM | protection by D-glucose 6-phosphate in presence of NAD+ | Pinus ponderosa | |
| PCMB | protection by D-glucose 6-phosphate in presence of NAD+ | Pinus ponderosa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.33 | - |
glucose 6-phosphate | - |
Pinus ponderosa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pinus ponderosa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Pinus ponderosa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pollen | - |
Pinus ponderosa | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, partially purified enzyme is stable for at least 6 months | Pinus ponderosa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Glucose 6-phosphate | - |
Pinus ponderosa | L-myo-Inositol 1-phosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.3 | 7.8 | - |
Pinus ponderosa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | required | Pinus ponderosa | |
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