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Literature summary for 5.5.1.4 extracted from
- 1L-myo-Inositol-1-phosphate synthase (1997), Biochim. Biophys. Acta, 1348, 245-256.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Phaseolus vulgaris |
- |
Saccharomyces cerevisiae |
- |
Arabidopsis thaliana |
- |
Entamoeba histolytica |
- |
Brassica napus |
- |
Candida albicans |
- |
Mesembryanthemum crystallinum |
- |
Citrus x paradisi |
- |
Spirodela polyrhiza |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Homo sapiens | |
| additional information | - |
additional information | - |
Rattus norvegicus | |
| additional information | - |
additional information | - |
Saccharomyces cerevisiae | |
| additional information | - |
additional information | - |
Bos taurus | |
| additional information | - |
additional information | - |
Euglena gracilis | |
| additional information | - |
additional information | - |
Neurospora crassa | |
| additional information | - |
additional information | - |
Vigna radiata | |
| additional information | - |
additional information | - |
Acer pseudoplatanus | |
| additional information | - |
additional information | - |
Lilium longiflorum | |
| additional information | - |
additional information | - |
Lemna gibba | |
| additional information | - |
additional information | - |
Arthrospira platensis | |
| additional information | - |
additional information | - |
Pinus ponderosa |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Phaseolus vulgaris | 9507 | - |
| chloroplast | - |
Euglena gracilis | 9507 | - |
| chloroplast | - |
Vigna radiata | 9507 | - |
| cytosol | - |
Euglena gracilis | 5829 | - |
| cytosol | - |
Vigna radiata | 5829 | - |
| cytosol | - |
Arthrospira platensis | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 45000 | - |
3 * 45000, SDS-PAGE in presence of 2-mercaptoethanol | Lemna gibba |
| 46249 | - |
x * 46249, calculation from nucleotide sequence | Brassica napus |
| 54500 | - |
4 * 54500 | Bos taurus |
| 56337 | - |
x * 56337, calculation from nucleotide sequence | Citrus x paradisi |
| 56388 | - |
x * 56388, calculation from nucleotide sequence | Spirodela polyrhiza |
| 56529 | - |
x * 56529, calculation from nucleotide sequence | Phaseolus vulgaris |
| 56685 | - |
x * 56685, calculation from nucleotide sequence | Entamoeba histolytica |
| 56761 | - |
x * 56761, calculation from nucleotide sequence | Mesembryanthemum crystallinum |
| 58000 | - |
4 * 58000 | Vigna radiata |
| 61000 | - |
3 * 61000 | Lilium longiflorum |
| 61000 | - |
3 * 61000, cytosolic enzyme, SDS-PAGE | Euglena gracilis |
| 62000 | - |
4 * 62000, chloroplastic enzyme | Euglena gracilis |
| 62000 | - |
4 * 62000 | Saccharomyces cerevisiae |
| 65000 | - |
4 * 65000 | Neurospora crassa |
| 67000 | - |
3 * 67000, cytosolic enzyme, SDS-PAGE | Arthrospira platensis |
| 68000 | - |
4 * 68000, testis | Rattus norvegicus |
| 135000 | - |
gel filtration | Lemna gibba |
| 150000 | - |
- |
Acer pseudoplatanus |
| 155000 | - |
- |
Pinus ponderosa |
| 157000 | - |
gel filtration | Lilium longiflorum |
| 159000 | - |
gel filtration | Hevea brasiliensis |
| 165000 | - |
gel filtration | Homo sapiens |
| 165000 | - |
gel filtration | Rattus norvegicus |
| 179000 | - |
cytosolic enzyme, gel filtration | Euglena gracilis |
| 200300 | - |
cytosolic enzyme, gel filtration | Arthrospira platensis |
| 210000 | - |
testis, gel filtration, PAGE, ultracentrifugal equilibrium sedimentation | Rattus norvegicus |
| 218000 | - |
testis | Bos taurus |
| 240000 | - |
gel filtration | Saccharomyces cerevisiae |
| 248000 | - |
chloroplastic enzyme, gel filtration | Euglena gracilis |
| 260000 | - |
- |
Neurospora crassa |
| 260000 | - |
- |
Streptomyces sp. |
| 266000 | - |
chloroplastic enzyme, gel filtration | Vigna radiata |
| 290000 | - |
mammary gland, gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Glucose 6-phosphate | Phaseolus vulgaris | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? |  |
| D-Glucose 6-phosphate | Homo sapiens | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Rattus norvegicus | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Saccharomyces cerevisiae | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Bos taurus | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Euglena gracilis | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Neurospora crassa | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Arabidopsis thaliana | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Entamoeba histolytica | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Brassica napus | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Vigna radiata | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Candida albicans | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Acer pseudoplatanus | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Streptomyces sp. | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Lilium longiflorum | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Mesembryanthemum crystallinum | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Lemna gibba | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Hevea brasiliensis | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Arthrospira platensis | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Pinus ponderosa | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Citrus x paradisi | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
| D-Glucose 6-phosphate | Spirodela polyrhiza | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acer pseudoplatanus | - |
- |
- |
| Arabidopsis thaliana | - |
- |
- |
| Arthrospira platensis | - |
- |
- |
| Bos taurus | - |
- |
- |
| Brassica napus | - |
- |
- |
| Candida albicans | - |
- |
- |
| Citrus x paradisi | - |
- |
- |
| Entamoeba histolytica | - |
- |
- |
| Euglena gracilis | - |
- |
- |
| Hevea brasiliensis | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Lemna gibba | - |
- |
- |
| Lilium longiflorum | - |
- |
- |
| Mesembryanthemum crystallinum | - |
- |
- |
| Neurospora crassa | - |
- |
- |
| Phaseolus vulgaris | - |
- |
- |
| Pinus ponderosa | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
| Spirodela polyrhiza | - |
- |
- |
| Streptomyces sp. | - |
- |
- |
| Vigna radiata | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| brain | fetal | Homo sapiens | - |
| mammary gland | - |
Rattus norvegicus | - |
| pollen | - |
Lilium longiflorum | - |
| pollen | - |
Pinus ponderosa | - |
| testis | - |
Rattus norvegicus | - |
| testis | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Glucose 6-phosphate | - |
Phaseolus vulgaris | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Homo sapiens | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Rattus norvegicus | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Saccharomyces cerevisiae | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Bos taurus | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Euglena gracilis | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Neurospora crassa | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Arabidopsis thaliana | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Entamoeba histolytica | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Brassica napus | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Vigna radiata | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Candida albicans | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Acer pseudoplatanus | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Streptomyces sp. | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Lilium longiflorum | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Mesembryanthemum crystallinum | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Lemna gibba | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Hevea brasiliensis | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Arthrospira platensis | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Pinus ponderosa | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Citrus x paradisi | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | - |
Spirodela polyrhiza | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Phaseolus vulgaris | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Homo sapiens | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Rattus norvegicus | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Saccharomyces cerevisiae | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Bos taurus | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Euglena gracilis | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Neurospora crassa | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Arabidopsis thaliana | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Entamoeba histolytica | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Brassica napus | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Vigna radiata | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Candida albicans | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Acer pseudoplatanus | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Streptomyces sp. | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Lilium longiflorum | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Mesembryanthemum crystallinum | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Lemna gibba | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Hevea brasiliensis | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Arthrospira platensis | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Pinus ponderosa | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Citrus x paradisi | ? | - |
? | |
| D-Glucose 6-phosphate | the enzyme catalyzes the first committed step in the production of all inositol containing compounds, including phospholipids | Spirodela polyrhiza | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | - |
Saccharomyces cerevisiae |
| ? | - |
Lilium longiflorum |
| ? | x * 46249, calculation from nucleotide sequence | Brassica napus |
| ? | x * 56761, calculation from nucleotide sequence | Mesembryanthemum crystallinum |
| ? | x * 56685, calculation from nucleotide sequence | Entamoeba histolytica |
| ? | x * 57781,calculation from nucleotide sequence | Candida albicans |
| ? | x * 56337, calculation from nucleotide sequence | Citrus x paradisi |
| ? | x * 56388, calculation from nucleotide sequence | Spirodela polyrhiza |
| ? | x * 56529, calculation from nucleotide sequence | Phaseolus vulgaris |
| tetramer | - |
Arthrospira platensis |
| tetramer | 4 * 68000, testis | Rattus norvegicus |
| tetramer | 4 * 65000 | Neurospora crassa |
| tetramer | 4 * 54500 | Bos taurus |
| tetramer | 4 * 58000 | Vigna radiata |
| tetramer | 4 * 62000, chloroplastic enzyme | Euglena gracilis |
| tetramer | 4 * 62000 | Saccharomyces cerevisiae |
| trimer | - |
Rattus norvegicus |
| trimer | 3 * 45000, SDS-PAGE in presence of 2-mercaptoethanol | Lemna gibba |
| trimer | 3 * 61000 | Lilium longiflorum |
| trimer | 3 * 61000, cytosolic enzyme, SDS-PAGE | Euglena gracilis |
| trimer | 3 * 67000, cytosolic enzyme, SDS-PAGE | Arthrospira platensis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Saccharomyces cerevisiae |
| 7.2 | - |
chloroplastic enzyme | Vigna radiata |
| 7.2 | - |
mammary gland | Rattus norvegicus |
| 7.3 | 7.8 | - |
Pinus ponderosa |
| 7.5 | - |
- |
Homo sapiens |
| 7.5 | - |
cytosolic enzyme | Euglena gracilis |
| 7.5 | - |
brain | Rattus norvegicus |
| 7.6 | - |
chloroplastic enzyme | Euglena gracilis |
| 7.7 | - |
- |
Neurospora crassa |
| 7.7 | - |
- |
Lemna gibba |
| 7.7 | - |
testis | Rattus norvegicus |
| 7.8 | - |
- |
Arthrospira platensis |
| 7.8 | 8.5 | - |
Lilium longiflorum |
| 8 | - |
- |
Acer pseudoplatanus |
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