Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-sorbitol 6-phosphate | - |
Rattus norvegicus | |
NaBH4 | partial inactivation in presence of NAD+. No inactivation in absence of NAD+ | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
215000 | - |
gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate | formation of 5-keto-D-glucose 6-phosphate as an enzyme-bound intermediate in the conversion of D-glucose 6-phosphate into 1L-myo-inositol 1-phosphate | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Glucose 6-phosphate | - |
Rattus norvegicus | L-myo-Inositol 1-phosphate | - |
? | |
additional information | after removal of tightly bound NAD+ the enzyme catalyzes the reduction of 5-keto-D-glucitol 6-phosphate and 5-keto-D-glucose 6-phosphate by NADH to give glucitol 6-phosphate and glucose 6-phosphate respectively | Rattus norvegicus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | tightly bound | Rattus norvegicus | |
NAD+ | Km: 0.05 mM | Rattus norvegicus |