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Literature summary for 5.4.99.B4 extracted from

  • O’Connor, M.; Gregory, S.T.
    Inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function in wild-type Escherichia coli and Salmonella enterica (2011), J. Bacteriol., 193, 154-162.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
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Salmonella enterica
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serovar typhimurium
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
23S rRNA uridine pseudouridine synthase is responsible for the pseudouridine modifications at positions 1911, 1915, and 1917 in helix 69 of 23S rRNA Escherichia coli 23S rRNA pseudouridine
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?
23S rRNA uridine pseudouridine synthase is responsible for the pseudouridine modifications at positions 1911, 1915, and 1917 in helix 69 of 23S rRNA Salmonella enterica 23S rRNA pseudouridine
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?

Synonyms

Synonyms Comment Organism
pseudouridine synthase
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Escherichia coli
pseudouridine synthase
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Salmonella enterica
Rlu
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Escherichia coli
Rlu
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Salmonella enterica

General Information

General Information Comment Organism
malfunction inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function Salmonella enterica
malfunction inactivation of the RluD pseudouridine synthase has minimal effects on growth and ribosome function. Deletion of rluD is associated with extremely slow growth, increased readthrough of stop codons, and defects in 50S ribosomal subunit assembly and 30S-50S subunit association Escherichia coli