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Literature summary for 5.4.99.B22 extracted from

  • Behm-Ansmant, I.; Massenet, S.; Immel, F.; Patton, J.R.; Motorin, Y.; Branlant, C.
    A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs (2006), RNA, 12, 1583-1593.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.4.99.B22

Cloned(Commentary)

Cloned (Comment) Organism
-
 Saccharomyces cerevisiae
expression in Saccharomyces cerevisiae Mus musculus

Protein Variants

Protein Variants Comment Organism
D112A inactive mutant enzyme Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Saccharomyces cerevisiae Q12211
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
-
 Saccharomyces cerevisiae

Reaction

Reaction Comment Organism Reaction ID
tRNA uridine26 = tRNA pseudouridine26 (1) Saccharomyces cerevisiae
a
tRNA uridine27 = tRNA pseudouridine27 (2) Saccharomyces cerevisiae
a
tRNA uridine28 = tRNA pseudouridine28 (3) Saccharomyces cerevisiae
a
tRNA uridine30 = tRNA pseudouridine30 (4) Saccharomyces cerevisiae
a
tRNA uridine34 = tRNA pseudouridine34 (5) Saccharomyces cerevisiae
a
tRNA uridine35 = tRNA pseudouridine35 (6) Saccharomyces cerevisiae
a
tRNA uridine36 = tRNA pseudouridine36 (7) Saccharomyces cerevisiae
a
tRNA uridine65 = tRNA pseudouridine65 (8) Saccharomyces cerevisiae
a
tRNA uridine67 = tRNA pseudouridine67 (9) Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information does not pseudouridylate uridine30 Mus musculus ?
-
 ?
pre-tRNAIle(UAU) uridine27
-
 Mus musculus pre-tRNAIle(UAU) pseudouridine27
-
 ?
pre-tRNAIle(UAU) uridine30
-
 Mus musculus pre-tRNAIle(UAU) pseudouridine30
-
 ?
pre-tRNAIle(UAU) uridine34
-
 Mus musculus pre-tRNAIle(UAU) pseudouridine34
-
 ?
pre-tRNAIle(UAU) uridine36
-
 Mus musculus pre-tRNAIle(UAU) pseudouridine36
-
 ?
tRNAArg(ACG) uridine1 Pus1p can catalyze pseudouridine1 formation in the mature tRNAArg, the pre-tRNAArg, and its maturation intermediates Mus musculus tRNAArg(ACG) pseudouridine1
-
 ?
tRNAArg(ACG) uridine1 Pus1p can catalyze pseudouridine1 formation in the mature tRNAArg, the pre-tRNAArg, and its maturation intermediates Saccharomyces cerevisiae tRNAArg(ACG) pseudouridine1
-
 ?
tRNATrp(CCA) uridine26 low activity Mus musculus tRNATrp(CCA) pseudouridine26
-
 ?
tRNATrp(CCA) uridine27
-
 Mus musculus tRNATrp(CCA) pseudouridine27
-
 ?
tRNATrp(CCA) uridine28 low activity Mus musculus tRNATrp(CCA) pseudouridine28
-
 ?

Synonyms

Synonyms Comment Organism
mPus1p
-
 Mus musculus
Pus1p
-
 Mus musculus
Pus1p
-
 Saccharomyces cerevisiae
RNA:pseudouridine synthases 1
-
 Mus musculus
RNA:pseudouridine synthases 1
-
 Saccharomyces cerevisiae
scPus1p
-
 Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Mus musculus