Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.4.99.9 extracted from

  • Borrelli, S.; Zandberg, W.F.; Mohan, S.; Ko, M.; Martinez-Gutierrez, F.; Partha, S.K.; Sanders, D.A.; Av-Gay, Y.; Pinto, B.M.
    Antimycobacterial activity of UDP-galactopyranose mutase inhibitors (2010), Int. J. Antimicrob. Agents, 36, 364-368.
    View publication on PubMed
Search for more literature for 5.4.99.9

Inhibitors

Inhibitors Comment Organism Structure
(4-chlorophenyl)-[1-(4-chlorophenyl)-3-hydroxy-5-methyl-1H-pyrazol-4-yl]-methanone
-
 Klebsiella pneumoniae
(4-chlorophenyl)-[1-(4-chlorophenyl)-3-hydroxy-5-methyl-1H-pyrazol-4-yl]-methanone
-
 Mycobacterium tuberculosis
3-(4-iodophenyl)-2-[4-(3,4-dichlorophenyl)-thiazol-2-ylamino]-propionic acid
-
 Klebsiella pneumoniae
3-(4-iodophenyl)-2-[4-(3,4-dichlorophenyl)-thiazol-2-ylamino]-propionic acid
-
 Mycobacterium tuberculosis
ethambutol
-
 Klebsiella pneumoniae
ethambutol
-
 Mycobacterium tuberculosis
Quinine
-
 Klebsiella pneumoniae
Quinine
-
 Mycobacterium tuberculosis
UDP
-
 Klebsiella pneumoniae
UDP
-
 Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
-
-
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis H37Rv
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-D-galactopyranose
-
 Klebsiella pneumoniae UDP-D-galactofuranose
-
 ?
UDP-D-galactopyranose
-
 Mycobacterium tuberculosis UDP-D-galactofuranose
-
 ?
UDP-D-galactopyranose
-
 Mycobacterium tuberculosis H37Rv UDP-D-galactofuranose
-
 ?

Synonyms

Synonyms Comment Organism
UGM
-
 Klebsiella pneumoniae
UGM
-
 Mycobacterium tuberculosis

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Klebsiella pneumoniae
FAD
-
 Mycobacterium tuberculosis

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0072
-
 pH and temperature not specified in the publication Klebsiella pneumoniae 3-(4-iodophenyl)-2-[4-(3,4-dichlorophenyl)-thiazol-2-ylamino]-propionic acid
0.037
-
 pH and temperature not specified in the publication Mycobacterium tuberculosis 3-(4-iodophenyl)-2-[4-(3,4-dichlorophenyl)-thiazol-2-ylamino]-propionic acid
0.044
-
 pH and temperature not specified in the publication Klebsiella pneumoniae (4-chlorophenyl)-[1-(4-chlorophenyl)-3-hydroxy-5-methyl-1H-pyrazol-4-yl]-methanone
0.062
-
 pH and temperature not specified in the publication Mycobacterium tuberculosis (4-chlorophenyl)-[1-(4-chlorophenyl)-3-hydroxy-5-methyl-1H-pyrazol-4-yl]-methanone