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Literature summary for 5.4.99.7 extracted from

  • Sawai, S.; Akashi, T.; Sakurai, N.; Suzuki, H.; Shibata, D.; Ayabe, S.; Aoki, T.
    Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes (2006), Plant Cell Physiol., 47, 673-677.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
N478H/V482I change of amino acids crucial for specificity to the cycloartenol synthase type. Mutant produces 4% lanosterol, 83% parkeol, and 13% cycloartenol from substrate (S)-2,3-epoxysqualene Lotus japonicus

Organism

Organism UniProt Comment Textmining
Lotus japonicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-2,3-epoxysqualene
-
Lotus japonicus lanosterol synthesis of about 0.1% parkeol as byproduct ?