Literature summary for 5.4.99.7 extracted from

Sakano, Y.; Mutsuga, M.; Tanaka, R.; Suganuma, H.; Inakuma, T.; Toyoda, M.; Goda, Y.; Shibuya, M.; Ebizuka, Y.
Inhibition of human lanosterol synthase by the constituents of Colocasia esculenta (taro) (2005), Biol. Pharm. Bull., 28, 299-304.

Search for more literature for 5.4.99.7

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Saccharomyces cerevisiae	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
ethanol extract from Angelica keiskei leaves	11% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Basella rubra leaves	5% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Chrysanthemum morifolium flowers	13% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Chrysanthemum morifolium leaves	7% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Colocasia esculenta rhizomes	55% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Cryptotaenia japonica leaves	10% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Glycine max immature seeds	14% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Oenanthe stolonifera leaves	13% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Perilla frutescens leaves	5% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Petasites japonicus buds	6% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Zingiber officinale buds	14% inhibition at 0.3 mg/ml	Homo sapiens
ethanol extract from Zingiber officinale rhizomes	6% inhibition at 0.3 mg/ml	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(3S)-2,3-oxidosqualene	Homo sapiens	-	lanosterol	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(3S)-2,3-oxidosqualene	-	Homo sapiens	lanosterol	-	?

Synonyms

Synonyms	Comment	Organism
lanosterol synthase	-	Homo sapiens
OSC	-	Homo sapiens

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Release 2023.1 (January 2023)