Activating Compound | Comment | Organism | Structure |
---|---|---|---|
tryptophan | heterotrophic positive effector | Ogataea angusta | |
tryptophan | heterotrophic positive effector | Saccharomyces cerevisiae |
Cloned (Comment) | Organism |
---|---|
expression in a Saccharomyces cerevisiae aro7DELTA strain | Ogataea angusta |
overexpression in Hansenula polymorpha | Ogataea angusta |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tyrosine | heterotrophic feedback inhibitor | Ogataea angusta | |
tyrosine | heterotrophic feedback inhibitor | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | sigmoid substrate saturation curve with S0.5: 16.7 mM for chorismate at 37°C and S0.5: 12 mM for chorismate at 37°C in presence of 0.1 mM tyrosine | Ogataea angusta | |
1.6 | - |
chorismate | 37°C, in presence of 0.01 mM tryptophan | Ogataea angusta |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
32000, SDS-PAGE | Ogataea angusta |
70000 | - |
PAGE | Ogataea angusta |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | Ogataea angusta | biosynthesis of aromatic amino acids | Prephenate | - |
? | |
Chorismate | Saccharomyces cerevisiae | biosynthesis of aromatic amino acids | Prephenate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ogataea angusta | Q9P4D8 | - |
- |
Saccharomyces cerevisiae | P32178 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Ogataea angusta |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
168 | - |
Superdex 200pg pool | Ogataea angusta |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | - |
Ogataea angusta | Prephenate | - |
? | |
Chorismate | - |
Saccharomyces cerevisiae | Prephenate | - |
? | |
Chorismate | biosynthesis of aromatic amino acids | Ogataea angusta | Prephenate | - |
? | |
Chorismate | biosynthesis of aromatic amino acids | Saccharomyces cerevisiae | Prephenate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 32000, SDS-PAGE | Ogataea angusta |
Synonyms | Comment | Organism |
---|---|---|
chorismate mutase | - |
Ogataea angusta |
chorismate mutase | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
38 | - |
decrease in turnover at temperatures higher than 38°C | Saccharomyces cerevisiae |
48 | - |
maximum enzymatic activity | Ogataea angusta |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
23.8 | - |
chorismate | 37°C, in presence of 0.1 mM tyrosine | Ogataea angusta | |
89.3 | - |
chorismate | 37°C, in presence of 0.1 mM tyrosine | Ogataea angusta | |
367 | - |
chorismate | 37°C | Ogataea angusta |