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Literature summary for 5.4.99.2 extracted from

  • Dybala-Defratyka, A.; Paneth, P.; Banerjee, R.; Truhlar, D.G.
    Coupling of hydrogenic tunneling to active-site motion in the hydrogen radical transfer catalyzed by a coenzyme B12-dependent mutase (2007), Proc. Natl. Acad. Sci. USA, 104, 10774-10779.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Propionibacterium freudenreichii subsp. shermanii
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Reaction

Reaction Comment Organism Reaction ID
(R)-methylmalonyl-CoA = succinyl-CoA intrinsic hydrogen isotope effect is 51 due to multidimensional tunneling. Corner-cutting tunneling decreases the distance over which the system tunnels without a comparable increase in either the effective potential barrier or the effective mass for tunneling Propionibacterium freudenreichii subsp. shermanii