Literature summary for 5.4.4.2 extracted from

Ogawa, D.; Nakajima, N.; Tamaoki, M.; Aono, M.; Kubo, A.; Kamada, H.; Saji, H.
The isochorismate pathway is negatively regulated by salicylic acid signaling in O3-exposed Arabidopsis (2007), Planta, 226, 1277-1285.

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Activating Compound

Activating Compound	Comment	Organism	Structure
O3	exposure to O3 enhances the accumulation of salicylic acid and increases enzyme activity, but does not affect phenylalanine ammonia lyase activity. Treatment of plants suppresses the enhancement of enzyme expression by O3	Arabidopsis thaliana

Protein Variants

Protein Variants	Comment	Organism
additional information	plants defective in enzyme activity due to mutation sid2, level of salicylic acid and the activity of enzyme do not increase in response to O3 exposure	Arabidopsis thaliana

Inhibitors

Inhibitors	Comment	Organism	Structure
salicylic acid	treatment of plants suppresses the enhancement of enzyme expression by O3	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	-	-

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Release 2023.1 (January 2023)