Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.4.3.2 extracted from

  • Frey, P.A.; Ballinger, M.D.; Reed, G.H.
    S-Adenosylmethionine: a "poor man's coenzyme B12" in the reaction of lysine 2,3-aminomutase (1998), Biochem. Soc. Trans., 26, 304-310.
    View publication on PubMed
Search for more literature for 5.4.3.2

Activating Compound

Activating Compound Comment Organism Structure
S-adenosylmethionine required Clostridium sp.
S-adenosylmethionine plays a role in lysine 2,3-aminomutase reaction Clostridium sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ Fe-S cluster is required as cofactor Clostridium sp.
Fe2+ contains [4Fe-4S] clusters Clostridium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Lys Clostridium sp. production of (3S)-3,6-diaminohexanoic acid for the biosynthesis of antibiotics ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium sp.
-
-
-

Reaction

Reaction Comment Organism Reaction ID
L-lysine = (3S)-3,6-diaminohexanoate mechanism of radical rearrangement in the reaction Clostridium sp.
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Lys
-
 Clostridium sp. (3S)-3,6-diaminohexanoic acid
-
 ?
L-Lys production of (3S)-3,6-diaminohexanoic acid for the biosynthesis of antibiotics Clostridium sp. ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate required Clostridium sp.
pyridoxal 5'-phosphate role in lysine 2,3-aminomutase reaction Clostridium sp.