Literature summary for 5.4.2.8 extracted from

Xu, J.; Sarma, A.V.S.; Wei, Y.; Beamer, L.J.; Van Doren, S.R.
Multiple ligand-bound states of a phosphohexomutase revealed by principal component analysis of NMR peak shifts (2017), Sci. Rep., 7, 5343 .

Search for more literature for 5.4.2.8

Protein Variants

Protein Variants	Comment	Organism
S108C	inactive	Pseudomonas aeruginosa

Inhibitors

Inhibitors	Comment	Organism	Structure
alpha-D-Glucose 1,6-bisphosphate	-	Pseudomonas aeruginosa
alpha-D-glucose 1-phosphate	-	Pseudomonas aeruginosa
D-xylose 1-phosphate	-	Pseudomonas aeruginosa

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
alpha-D-glucose 1-phosphate	Pseudomonas aeruginosa	-	D-glucose 6-phosphate	-	r
alpha-D-mannose 1-phosphate	Pseudomonas aeruginosa	-	D-mannose 6-phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	P26276	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	the enzyme requires conserved phosphoserine 108 for activity	Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
alpha-D-glucose 1-phosphate	-	Pseudomonas aeruginosa	D-glucose 6-phosphate	-	r
alpha-D-mannose 1-phosphate	-	Pseudomonas aeruginosa	D-mannose 6-phosphate	-	r

Subunits

Subunits	Comment	Organism
?	x * 52000, SDS-PAGE	Pseudomonas aeruginosa

Synonyms

Synonyms	Comment	Organism
alpha-D-phosphohexomutase	-	Pseudomonas aeruginosa
Phosphohexomutase	-	Pseudomonas aeruginosa
phosphomannomutase/phosphoglucomutase	-	Pseudomonas aeruginosa
PMM/PGM	-	Pseudomonas aeruginosa

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Release 2023.1 (January 2023)