Literature summary for 5.4.2.8 extracted from

Yang, Y.H.; Song, E.; Park, S.H.; Kim, J.N.; Lee, K.; Kim, E.; Kim, Y.G.; Kim, B.G.
Loss of phosphomannomutase activity enhances actinorhodin production in Streptomyces coelicolor (2010), Appl. Microbiol. Biotechnol., 86, 1485-1492.

Search for more literature for 5.4.2.8

Cloned(Commentary)

Cloned (Comment)	Organism
the vectors pET24ma, pIBR25 and pKC1139 are used	Streptomyces coelicolor

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	a deletion mutant is constructed	Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
alpha-D-mannose 1-phosphate	Streptomyces coelicolor	-	D-mannose 6-phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Streptomyces coelicolor	Q9KZL6	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
alpha-D-mannose 1-phosphate	-	Streptomyces coelicolor	D-mannose 6-phosphate	-	r

Synonyms

Synonyms	Comment	Organism
ManB	-	Streptomyces coelicolor
phosphomannomutase	-	Streptomyces coelicolor
PMM	-	Streptomyces coelicolor

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	activity assay	Streptomyces coelicolor

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	activity assay	Streptomyces coelicolor

General Information

General Information	Comment	Organism
physiological function	phosphomannomutase is important in the direct or/and indirect control of antibiotic production	Streptomyces coelicolor

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Release 2023.1 (January 2023)