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Literature summary for 5.4.2.6 extracted from

  • Dai, J.; Wang, L.; Allen, K.N.; Radstrom, P.; Dunaway-Mariano, D.
    Conformational cycling in beta-phosphoglucomutase catalysis: reorientation of the beta-D-glucose 1,6-(bis)phosphate intermediate (2006), Biochemistry, 45, 7818-7824.
    View publication on PubMed
Search for more literature for 5.4.2.6

Activating Compound

Activating Compound Comment Organism Structure
beta-D-glucose 1,6-bisphosphate required, Km value 0.0065 mM. Beta-D-glucose 1,6-bisphosphate is a reaction intermediate Lactococcus lactis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.049
-
 beta-D-glucose 1-phosphate pH 7.0, 25°C Lactococcus lactis

Organism

Organism UniProt Comment Textmining
Lactococcus lactis
-
-
-

Reaction

Reaction Comment Organism Reaction ID
beta-D-Glucose 1-phosphate = beta-D-glucose 6-phosphate phosphoryl transfer rather than ligand binding is rate-limiting. Beta-D-glucose 1,6-bisphosphate is a reaction intermediate and binds to the active site in two different orientations with roughly the same efficiency. Reorientation of the beta-D-glucose 1,6-bisphosphate intermediate occurs by diffusion into solvent followed by binding in the opposite orientation Lactococcus lactis
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-D-Glucose 1-phosphate
-
 Lactococcus lactis beta-D-Glucose 6-phosphate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
177
-
 beta-D-glucose 1-phosphate pH 7.0, 25°C Lactococcus lactis