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Literature summary for 5.4.2.11 extracted from

  • Ren, F.; Wu, H.; Lei, Y.; Zhang, H.; Liu, R.; Zhao, Y.; Chen, X.; Zeng, D.; Tong, A.; Chen, L.; Wei, Y.; Huang, C.
    Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma (2010), Mol. Cancer, 9, 81.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine PGAM1 plays an important role in hepatocarcinogenesis, is a potential diagnostic biomarker as well as an attractive therapeutic target for hepatocellular carcinoma Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28900
-
calculated from amino acid sequence Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-phospho-D-glycerate Homo sapiens
-
3-phospho-D-glycerate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P18669
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
Homo sapiens
-
hepatocellular carcinoma cell
-
Homo sapiens
-
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
Homo sapiens 3-phospho-D-glycerate
-
?

Synonyms

Synonyms Comment Organism
PGAM1
-
Homo sapiens
phosphoglycerate mutase 1
-
Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens calculated from amino acid sequence
-
6.7