Literature summary for 5.4.2.10 extracted from

Jolly, L.; Wu, S.; van Heijenoort, J.; De Lencastre, H.; Mengin-Lcreulx, D.; Tomasz, A.
The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phophoglucosamine mutase (1997), J. Bacteriol., 179, 5321-5325.

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Activating Compound

Activating Compound	Comment	Organism	Structure
D-glucose 1,6-diphosphate	100fold activation	Staphylococcus aureus

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in Escherichia coli	Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-glucoamine 6-phosphate	Staphylococcus aureus	involved in formation of cell-wall precursor UDP-N-acetylglucosamine	D-glucosamine 1-phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
to homogeneity, recombinant enzyme	Staphylococcus aureus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.1	-	-	Staphylococcus aureus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glucoamine 6-phosphate	involved in formation of cell-wall precursor UDP-N-acetylglucosamine	Staphylococcus aureus	D-glucosamine 1-phosphate	-	r

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Release 2023.1 (January 2023)