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Literature summary for 5.3.99.5 extracted from

  • Son, D.J.; Akiba, S.; Hong, J.T.; Yun, Y.P.; Hwang, S.Y.; Park, Y.H.; Lee, S.E.
    Piperine inhibits the activities of platelet cytosolic phospholipase A2 and thromboxane A2 synthase without affecting cyclooxygenase-1 activity different mechanisms of action are involved in the inhibition of platelet aggregation and macrophage inflammatory response (2014), Nutrients, 6, 3336-3352 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
imidazole
-
Oryctolagus cuniculus
piperine significant inhibition at 0.3 mM Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prostaglandin H2 Oryctolagus cuniculus
-
thromboxane A2
-
?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prostaglandin H2
-
Oryctolagus cuniculus thromboxane A2
-
?

Synonyms

Synonyms Comment Organism
thromboxane A2 synthase
-
Oryctolagus cuniculus
TXA2 synthase
-
Oryctolagus cuniculus