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Literature summary for 5.3.99.5 extracted from

  • Umemura, K.; Nakashima, M.; Saruta, T.
    Thromboxane A2 synthetase inhibition suppresses cough induced by angiotensin converting enzyme inhibitors (1997), Life Sci., 60, 1583-1588.
    View publication on PubMed

Application

Application Comment Organism
medicine thromboxane A2 may somehow mediate coughing induced by the angiotensin converting enzyme inhibitors. Patients on angiotensin converting enzyme inhibitors who develop cough may benefit from thromboxane A2 synthetase inhibitors Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2 i.e. PGH2 Homo sapiens thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
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