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Literature summary for 5.3.99.4 extracted from
- Expression of thromboxane synthase, prostacyclin synthase and thromboxane receptor in atherosclerotic lesions: correlation with plaque composition (2010), Atherosclerosis, 208, 376-381.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | Mus musculus | - |
Prostaglandin I2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aorta | atherosclerotic aorta | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Mus musculus | Prostaglandin I2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGIS | - |
Mus musculus |
| prostacyclin synthase | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | after 16 weeks the prostacyclin synthase mRNA levels are reduced | down |
| Mus musculus | after 8 weeks on fat diet, aortic arches from low-density lipoprotein receptor deficient, LDL r-KO, mice shows a significant increase in prostacyclin synthase levels | up |
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Release 2023.1 (January 2023)
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