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Literature summary for 5.3.99.4 extracted from

  • Wang, W.; Zolty, E.; Falk, S.; Summer, S.; Stearman, R.; Geraci, M.; Schrier, R.
    Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice (2007), Am. J. Physiol. Renal Physiol., 293, F1131-F1136.
    View publication on PubMed

Application

Application Comment Organism
medicine synthesis of prostaglandin by enzyme contributes to renal protection against endotoxemia-related acute kidney injury Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
specific transgenic expression in mouse kidney using rat KSP-cadherin promoter Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
additional information specific transgenic expression of prostacyclin synthase in mouse kidney results in increased in urinary 6-keto-prostaglandin F1alpha. Transgenic mice demonstrate endotoxemia-related acute kidney injury with low doses of lipopolysaccharide, which do not alter wild-type glomerular filtration rate. They also show increase in renal cAMP content Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q62969 expression in Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
Ptgis
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Rattus norvegicus