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Literature summary for 5.3.99.4 extracted from

  • Beitz, J.; Forster, W.
    Influence of human low density and high density lipoprotein cholesterol on the in vitro prostaglandin I2 synthetase activity (1980), Biochim. Biophys. Acta, 620, 352-355.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
High density lipoprotein cholesterol 1.0 mg/ml stimulates 21%. Lower concentrations inhibit, 16% inhibition by 0.25 mg/ml Sus scrofa
Low density lipoprotein cholesterol 0.5 mg/ml stimulates 27%. Inhibition at higher concentrations Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
Low density lipoprotein cholesterol 0.5 mg/ml stimulates 27%. Inhibition at higher concentrations. Maximal inhibition by 2 mg/ml, 64.2% Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Sus scrofa
-
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
Sus scrofa Prostaglandin I2 prostaglandin I2 ?