Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | increase in activity with increasing glutathione concentration from 0.1 mM up to 5 mM | Bos taurus | |
reduced glutathione | increase in activity with increasing glutathione concentration from 0.1 mM up to 5 mM | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tranylcypromine | 10 mM, 90% inhibition in absence or presence of 2 mM reduced glutathione | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Bos taurus | - |
- |
microsome | - |
Ovis aries | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Canis lupus familiaris | - |
- |
- |
Homo sapiens | - |
- |
- |
Ovis aries | - |
ram | - |
Oxidation Stability | Organism |
---|---|
the prostacyclin synthase is unusually sensitive to the redox state or sulfhydryl oxidation of the enzyme | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
coronary artery | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | - |
Homo sapiens | Prostaglandin I2 | prostaglandin I2 | ? | |
Prostaglandin H2 | - |
Bos taurus | Prostaglandin I2 | prostaglandin I2 | ? | |
Prostaglandin H2 | - |
Ovis aries | Prostaglandin I2 | prostaglandin I2 | ? | |
Prostaglandin H2 | - |
Canis lupus familiaris | Prostaglandin I2 | prostaglandin I2 | ? |