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Literature summary for 5.3.99.3 extracted from
- Microsomal prostaglandin E synthase-1 (mPGES-1) is the primary form of PGES expressed by the primate periovulatory follicle (2005), Hum. Reprod., 20, 1485-1492.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cPGES, expression analysis | Macaca fascicularis |
| expression analysis | Homo sapiens |
| mPGES-1, expression analysis | Macaca fascicularis |
| mPGES-2, expression analysis | Macaca fascicularis |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Macaca fascicularis | 5829 | - |
| microsome | - |
Homo sapiens | - |
- |
| microsome | - |
Macaca fascicularis | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | Macaca fascicularis | - |
Prostaglandin E2 | - |
? |  |
| Prostaglandin H2 | Homo sapiens | mPGES-1 is a gonadotropin-regulated enzyme | Prostaglandin E2 | - |
? | |
| Prostaglandin H2 | Macaca fascicularis | mPGES-1 is a gonadotropin-regulated enzyme | Prostaglandin E2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
women undergoing treatment for infertility, isozymes mPGES-2, mPGES-1, and cPGES | - |
| Macaca fascicularis | Q5DI74 | mPGES-1; cynomologus macaque, adult female, isozyme mPGES-1 | - |
| Macaca fascicularis | Q6PWL5 | cPGES; cynomologus macaque, adult female, isozyme cPGES | - |
| Macaca fascicularis | Q9N0A4 | mPGES-2, truncated form; cynomologus macaque, adult female, isozyme mPGES-2 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| corpus luteum | from women undergoing treatment for infertility, expression of mPGES-2, mPGES-1, and cPGES | Homo sapiens | - |
| granulosa cell | low level of cPGES | Macaca fascicularis | - |
| granulosa cell | low level of mPGES-2 | Macaca fascicularis | - |
| granulosa cell | mPGES-1 | Macaca fascicularis | - |
| mature ovarian follicle | expression of the primary form of PGES, mPGES-1 | Macaca fascicularis | - |
| additional information | tissue distribution of isozme expression, overview | Macaca fascicularis | - |
| additional information | tissue distribution of isozyme expression, overview | Macaca fascicularis | - |
| oocyte | - |
Macaca fascicularis | - |
| ovary | - |
Macaca fascicularis | - |
| theca cell | mPGES-1 | Macaca fascicularis | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Homo sapiens | Prostaglandin E2 | - |
? | |
| Prostaglandin H2 | - |
Macaca fascicularis | Prostaglandin E2 | - |
? | |
| Prostaglandin H2 | mPGES-1 is a gonadotropin-regulated enzyme | Homo sapiens | Prostaglandin E2 | - |
? | |
| Prostaglandin H2 | mPGES-1 is a gonadotropin-regulated enzyme | Macaca fascicularis | Prostaglandin E2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CPGES | - |
Homo sapiens |
| CPGES | - |
Macaca fascicularis |
| cytosolic prostaglandin E(2) synthase | - |
Macaca fascicularis |
| cytosolic prostaglandin E(2) synthase-2 | - |
Homo sapiens |
| microsomal prostaglandin E(2) synthase-1 | - |
Homo sapiens |
| microsomal prostaglandin E(2) synthase-1 | - |
Macaca fascicularis |
| microsomal prostaglandin E(2) synthase-2 | - |
Homo sapiens |
| microsomal prostaglandin E(2) synthase-2 | - |
Macaca fascicularis |
| mPGES-1 | - |
Homo sapiens |
| mPGES-1 | - |
Macaca fascicularis |
| mPGES-2 | - |
Homo sapiens |
| mPGES-2 | - |
Macaca fascicularis |
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