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Literature summary for 5.3.99.2 extracted from
- Lipocalin-type prostaglandin D2 synthase reduces glucagon secretion in alpha TC-1 clone 6 cells via the DP1 receptor (2015), Biochem. Biophys. Rep., 4, 224-227 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | Mus musculus | - |
Prostaglandin D2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | O09114 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| alpha-TC1.6 cell | - |
Mus musculus | - |
| pancreatic islet | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Mus musculus | Prostaglandin D2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| L-PGDS | - |
Mus musculus |
| lipocalin-type prostaglandin D2 synthase | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | higher enzyme concentrations significantly reduce the secretion of glucagon in alpha cells, which may contribute to the pathogenesis of diabetes | Mus musculus |
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Release 2023.1 (January 2023)
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