Literature summary for 5.3.99.2 extracted from

Perduca, M.; Bovi, M.; Bertinelli, M.; Bertini, E.; Destefanis, L.; Carrizo, M.E.; Capaldi, S.; Monaco, H.L.
High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase (2014), Acta Crystallogr. Sect. D, 70, 2125-2138 .

Search for more literature for 5.3.99.2

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
mutant enzymes C65A/K59A, C65A, C65A/W54F, C65A/W112F and C65A/W54F/W112F hanging drop vapor diffusion method, using 0.2 M ammonium sulfate, 30% (w/v) PEG 4000	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
Prostaglandin H2	Homo sapiens	-	Prostaglandin D2	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P41222	-	-

Purification (Commentary)

Purification (Comment)	Organism
chitin column chromatography and Superdex G-75 gel filtration	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Prostaglandin H2	-	Homo sapiens	Prostaglandin D2	-	?

Synonyms

Synonyms	Comment	Organism
L-PGDS	-	Homo sapiens
lipocalin-type prostaglandin d synthase	-	Homo sapiens
Prostaglandin-H2 D-isomerase	-	Homo sapiens

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Release 2023.1 (January 2023)