Any feedback?
Literature summary for 5.3.99.2 extracted from
- Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice (2009), Neuroscience, 163, 296-307.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the results demonstrate that the neuroprotective effects of hematopoietic prostaglandin D synthase in the model are mediated by suppression of activation and infiltration of inflammatory cells | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-benzhydryloxy-1-[3-(1H-tetrazol-5-yl)-propyl]piperidine | HQL-79 | Mus musculus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 26000 | - |
determined by SDS-PAGE and Western Blot analysis | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | Mus musculus | - |
Prostaglandin D2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | ischemic region, contralateral cortex | Mus musculus | - |
| microglia | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Mus musculus | Prostaglandin D2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Hematopoietic prostaglandin D synthase | - |
Mus musculus |
| HPGDS | - |
Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
