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Literature summary for 5.3.99.2 extracted from

  • Saleem, S.; Shah, Z.A.; Urade, Y.; Dore, S.
    Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia (2009), Neuroscience, 160, 248-254.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.99.2

Application

Application Comment Organism
medicine L-PGDS is beneficial for protecting the brain against transient and permanent cerebral ischemia, these results provide a better understanding of the role played by the enzymes that control eicosanoid synthesis and how they can be utilized as potential targets to prevent damage following either acute or potentially chronic neurological disorders Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Prostaglandin H2 Mus musculus
-
 Prostaglandin D2
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
central nervous system
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Mus musculus Prostaglandin D2
-
 ?

Synonyms

Synonyms Comment Organism
L-PGDS
-
 Mus musculus
lipocalin-prostaglandin D synthase
-
 Mus musculus
lipocalin-type prostaglandin d synthase
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus L-PGDS knockout mice are generated down