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Literature summary for 5.3.99.2 extracted from

  • Shimura, C.; Satoh, T.; Igawa, K.; Aritake, K.; Urade, Y.; Nakamura, M.; Yokozeki, H.
    Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin (2010), Am. J. Pathol., 176, 227-237.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.99.2

Activating Compound

Activating Compound Comment Organism Structure
phorbol 12-myrisate 13-acetate
-
 Homo sapiens
thymic stromal lymphopoietin stimulates mRNA synthesis Homo sapiens

Application

Application Comment Organism
medicine dendritic cells in the epidermis and dermis are capable of functioning as an important source of PGD2 in the skin, thereby contributing to or regulating innate and/or acquired immune responses of the skin Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26000
-
 determined by SDS-PAGE and Western Blot analysis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Prostaglandin H2 Homo sapiens
-
 Prostaglandin D2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
dendritic cell
-
 Homo sapiens
-
dermal dendritic cell
-
 Homo sapiens
-
Langerhans cell epidermal Langerhans cell Homo sapiens
-
myeloid dendritic cell
-
 Homo sapiens
-
plasmacytoid dendritic cell
-
 Homo sapiens
-
skin
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Homo sapiens Prostaglandin D2
-
 ?

Synonyms

Synonyms Comment Organism
H-PGDS
-
 Homo sapiens
Hematopoietic prostaglandin D synthase
-
 Homo sapiens
Prostaglandin D synthase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens lipopolysaccharide, LPS, reduces H-PGDS expression down