Literature summary for 5.3.99.2 extracted from

Huang, Y.C.; Lyu, R.K.; Tseng, M.Y.; Chang, H.S.; Hsu, W.C.; Kuo, H.C.; Chu, C.C.; Wu, Y.R.; Ro, L.S.; Huang, C.C.; Chen, C.M.
Decreased intrathecal synthesis of prostaglandin D(2) synthase in the cerebrospinal fluid of patients with acute inflammatory demyelinating polyneuropathy (2009), J. Neuroimmunol., 206, 100-105.

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Application

Application	Comment	Organism
medicine	in patients with acute inflammatory demyelinating polyneuropathy, concentration of prostaglandin-D synthase is significantly increased in cerebrospinal fluid, due to a blood-cerebrospinal fluid barrier dysfunction. The intrathecal synthesis of prostaglandin-D synthase is significantly decreased in these patients. Changes of the ratio of cerebrospinal fluid prostaglandin-D synthase to albumin are only observed in patients with acute inflammatory demyelinating polyneuropathy, but not in Miller Fisher Syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, or multiple sclerosis patients	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with acute inflammatory demyelinating polyneuropathy	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)