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Literature summary for 5.3.99.2 extracted from

  • Fujimori, K.; Inui, T.; Uodome, N.; Kadoyama, K.; Aritake, K.; Urade, Y.
    Zebrafish and chicken lipocalin-type prostaglandin D synthase homologues: Conservation of mammalian gene structure and binding ability for lipophilic molecules, and difference in expression profile and enzyme activity (2006), Gene, 375, 14-25.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Mus musculus
-
Danio rerio
-
Gallus gallus

Protein Variants

Protein Variants Comment Organism
G59C C59 is an essential residue for enzyme activity in mammals. Mutant G59C does not show enzymic activity Danio rerio
additional information chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184, shows weak enzymic activity Mus musculus
additional information chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184, shows weak enzymic activity Danio rerio

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28600
-
x * 28600, calculated Danio rerio

Organism

Organism UniProt Comment Textmining
Danio rerio Q8QGV4 homologue of lipocalin-type prostaglandin synthase, no enzymic activity
-
Gallus gallus Q8QFM7 homologue of lipocalin-type prostaglandin synthase, weak enzymic activity
-
Mus musculus
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
11.7
-
pH 8.0, 25°C Gallus gallus
14.9
-
chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184 Mus musculus
14.9
-
chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184 Danio rerio
434
-
wild-type, pH 8.0, 25°C Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate
-
Mus musculus (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
-
?
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate
-
Gallus gallus (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
-
?

Subunits

Subunits Comment Organism
? x * 28600, calculated Danio rerio