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Literature summary for 5.3.4.1 extracted from

  • Lin, L.; Gopal, S.; Sharda, A.; Passam, F.; Bowley, S.R.; Stopa, J.; Xue, G.; Yuan, C.; Furie, B.C.; Flaumenhaft, R.; Huang, M.; Furie, B.
    Quercetin-3-rutinoside inhibits protein disulfide isomerase by binding to its b'x domain (2015), J. Biol. Chem., 290, 23543-23552 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.4.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Origami B (DE3) cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
isoquercetin
-
 Mus musculus
quercetin-3-rutinoside
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
complete His-Tag purification resin column chromatography and Superdex 200 gel filtration Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
ERp5
-
 Mus musculus
ERp57
-
 Mus musculus
ERp72
-
 Mus musculus
PDI
-
 Mus musculus
protein disulfide isomerase
-
 Mus musculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0123
-
 at pH 7.4 and 25°C Mus musculus quercetin-3-rutinoside
0.014
-
 at pH 7.4 and 25°C Mus musculus isoquercetin